Company Names, addresses, dates: ^1,2
  Simmonds & Co, 35 Cabell, Lynchburg VA (c.1890)
  S.J. Simmonds, Rivermont Ave, Lynchburg VA (c.1906)
  Rivermont Pharmacy, 1208 Rivermont Ave, Lynchburg VA (c.1907 - 1960+)

Notes:
The 1890 Lynchburg City directory lists a drugstore named "Simmonds & Co". I suspect this was owned by James Simmonds, who was listed in the 1870 US Census as a Physician living in Lynchburg.
His son was Sidney Johnston Simmonds (1862-1945)³, who appears to have started the Rivermont Pharmacy. The 1906 Era Druggists Directory lists him as a druggist on Rivermont Avenue, and subsequent directories refer to that drugstore as being called the Rivermont Pharmacy.
The Dec 31, 1904 edition of the Richmond Times Dispatch newspaper had an article on page 3 that said "S.J. Simmons, proprietor of the Rivermont Drug store ... was arrested to-day on the charge of selling cocaine illegally".
Simmonds shows up as a druggist in Lynchburg in the 1910 US Census, but in the 1920 US Census, it appears he moved to Arlington VA, where he continued his career as a druggist.
The Rivermont Pharmacy continues to show up in city directories at 1208 Rivermont Avenue long after Simmonds left. It's listed in the 1960 city directory, which is the latest directory I had access to.


Bottles:

This is a clear 5.4" bottle embossed: vertical: Rivermont Drug Store / S.J. SIMMONDS, PROP. base: PAT JUNE 17 88 / S.B.

This is a 3.5"x6" cardboard blotter with red and black printing that says: 'SKETOFAX' / AROMATIC CREAM / (picture of a mosquito and a tube of Sketofax cream) / ... / Supplied by: / R.P. / RIVERMONT PHARMACY / 1208 RIVERMONT AVE. - LYNCHBURG, VA. / ...