Company Names, addresses, dates:
  E. R. Hunter, 56 High Street, Portsmouth VA (1872)
  E. R. Hunter, 66 High Street, Portsmouth VA (1874-1875)
  Edward R. Hunter, High corner Middle Street, Portsmouth VA (1880-1882)
  Edward R. Hunter, 234 High Street, Portsmouth VA (1883-1885)

Notes:
Edward R. Hunter (c.1821-1884)² ran a drugstore in Portsmouth, VA. The dates listed above are based on my limited set of available Portsmouth City directories¹, so they don't show all the years his drugstore was in operation.
The 1860 US Census listed his occupation as a "Tutor", and the 1872 City directory listed him as a drugstore owner, so he apparently became a druggist between 1860 and 1872.


Bottles:

This is an aqua 3.5" BIM bottle embossed: horizontal: "ERH" logo vertical: E. R. HUNTER / DRUGGIST / PORTSMOUTH, VA. base: WT&CO / C