Company Names, addresses, dates1:
William Ryan, 221 3rd street SW (1878-1881,1887,1893-1894,1897-1913)
William Ryan, 219 3rd street SW (1895-1896)
James Ryan, 331 C street SW (1894-1905)
William H. Ryan is listed in DC directories under Saloons and Restaurants on and off from 1878 to 1913. He's listed as a bottler in the 1887 directory. The 1880 census lists 45-year-old James Ryan at 221 3rd Streen SW with an occupation of Restaurant keeper.
I can't find any directory listings for "Wm & J. Ryan", which is embossed on one of the bottles below. The 1880 census entry mentioned above lists a 20 year old son who's also named William Ryan, and a 20 year old nephew named James Ryan. It's possible that this James Ryan is the "J." embossed on the bottle. The directories list a Saloon owned by James Ryan at 331 C Street SW from 1894 to 1905, which might be that same James.
book # 621
This is an aqua 7" hutchinson bottle with stopper intact, marked:
round slugplate: WM RYAN / 221 3RD ST / S.W. / WASHINGTON, D.C.
book # 622
This is an aqua 9.3" blob top bottle marked:
round slugplate: WM & J. RYAN / 221 3RD ST / S.W. / WASHINGTON, D.C.