Company Names, addresses, dates:
  R.E. Wiley, North Main Street, Neapolis VA (1894) ¹
  R.E. Wiley & Co, 330 & 636 North Main Steet, Danville VA (1902) ²
  R.E. Wiley & Co, 334 & 636 North Main Steet, Danville VA (1904) ²

Notes:
Robert E. Wiley (1872-1922)³ had two drugstores in Danville, VA, located at 334 and 636 North Main Street².
In 1894, he had a single drug store on N Main Street near the Main Street bridge, in Neapolis, VA.¹ For a short time, North Danville was called Neapolis, so this may be referring to the store at 334 N Main Street in Danville.
The 1902 Danville city directory said "R E Wiley & Co" consisted of Robert E. Wiley and Frederick L. Chapman. Chapman apparently took over the 2 drugstores by 1906, and it was called the F.L. Chapman drug store in that year's city directory.
Wiley moved to Southern Pines, NC circa 1907, and opened a drug store there. He was the mayor of that town.³

More information about Danville drug stores is available at rdricketts blog.

Wiley & Co Bottles:

	Bottle on the left is 4.5" (2 oz) and bottle on the right is 3.75" (1 oz). They are both clear, embossed: horizontal: 3ii (right bottle says '3i') vertical: R.E. WILEY & CO. / DRUGGISTS / DANVILLE, VA. base: W.T.CO. / A / U.S.A.
	This is similar to the bottles above, but a slightly different style. It's a 3.5" clear bottle, embossed: vertical: R.E. WILEY & CO. / DRUGGISTS / DANVILLE, VA. base: W T CO / USA / PAT DEC 11 94

These are clear 4.6" (2 oz) and 3.9" (1 oz) bottles embossed: horizontal: 3ii (or 3i) vertical: R.E. WILEY / DRUGGIST / DANVILLE, VA. base (left bottle): C. L. CO. CO. (seems to be double-struck) base (right bottle): C. L. CO. CO. / I