Company Names, addresses, dates: ¹
  Jones' Drug Store, Greensboro Rd, Schoolfield VA (c.1917-c.1921)
  Jones & Copeland, Schoolfield VA (c.1921)
  Jones' Drug Store, W Main St, Schoolfield VA (c.1927-c.1931)
  Jones' Drug Store, Main St corner Augusta Ave, Schoolfield VA (c.1935-c.1943)
  Jones' Drug Store, W Main St, Schoolfield VA (c.1945-c.1954)

Notes:
Ebbert Ashby Jones (1877-1952) was a druggist in Schoolfield. ²
Schoolfield VA is a branch of Danville Virginia, and the Jones' Drug Store is listed in the Danville city directories. I don't have access to any city directories between 1908 and 1917, so the Jones' drug store likely started sometime in between those 2 years.¹
Likewise, the last year I see the Jones' Drug store is 1954, and it's not listed in the 1960 directory, so it likely went out of business between those 2 years.

There were other drugstores in Danville run by people named Jones but I have not found any relation between those Jones and the Jones that ran this drug store.
More information about Danville drug stores is available at rdricketts blog.

Bottles:

This is a 4" tall (1 oz) clear bottle embossed: in slug plate, horizontal: 3i in slug plate, vertical: JONES' DRUG STORE / PRESCRIPTION DRUGGIST / SCHOOLFIELD, VA.